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A very active weather pattern is set for the end of this week and the beginning of next week.
MISSOURI INTERSTATE CRASH INVOLVING 40-50 VEHICLES RESULTS IN AT LEAST FIVE DEAD: REPORT
![Gulf Coast severe storm threat](https://a57.foxnews.com/static.foxnews.com/foxnews.com/content/uploads/2022/03/1200/675/Gulf-Coast-Storm-Threat-1.png?ve=1&tl=1)
Gulf Coast severe storm threat (Credit: Fox News )
Strong-to-severe storms will fire up Friday from the southern Plains, across the Gulf Coast States, the Southeast and along the East Coast on Saturday.
![Southeast severe storm threat](https://a57.foxnews.com/static.foxnews.com/foxnews.com/content/uploads/2022/03/1200/675/Southeast-Storm-Threat-2.png?ve=1&tl=1)
Southeast severe storm threat (Credit: Fox News )
Hail, strong winds, heavy rain and tornadoes will all be possible, so please stay alert to the latest forecast details.
![East Coast severe storm threat](https://a57.foxnews.com/static.foxnews.com/foxnews.com/content/uploads/2022/03/1200/675/East-Storm-Threat.png?ve=1&tl=1)
East Coast severe storm threat (Credit: Fox News )
Where cold air has settled in across the Midwest and Great Lakes, snow and a wintry mix will make travel difficult.
![Western snow potential](https://a57.foxnews.com/static.foxnews.com/foxnews.com/content/uploads/2022/03/1200/675/West-Snow-Potential-1.png?ve=1&tl=1)
Western snow potential (Credit: Fox News)
Another cold front moves across the West Coast this weekend, bringing the next big storm to travel cross-country on Monday and Tuesday.
![U.S. severe weather set-up](https://a57.foxnews.com/static.foxnews.com/foxnews.com/content/uploads/2022/03/1200/675/Monday-Severe-Weather.png?ve=1&tl=1)
U.S. severe weather set-up (Credit: Fox News )
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Meanwhile, temperatures will be above average for the Northeast and mid-Atlantic region, before the cold front forces temperatures down to more seasonal levels.