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A house exploded in a rural area of eastern Missouri on Friday, killing two children, authorities said.
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Emergency responders were called just before 7:45 a.m. to a home in Defiance, about 40 miles west of St. Louis. Two children were trapped in the house, but the intense flames prevented responders from getting to them.
![St. Louis, Branson, Springfield crime](https://a57.foxnews.com/static.foxnews.com/foxnews.com/content/uploads/2022/06/1200/675/ALL_CUSTOM_FS_LOCAL_NEWS_MO_CRIME.png?ve=1&tl=1)
Two children were killed Friday in a Defiance, Missouri, home explosion. (Fox News Digital)
Two adults who lived in the home survived, authorities said. One suffered a minor injury and was treated at the scene. The other wasn't hurt.
A St. Charles County police officer also was treated for a minor injury.
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The cause of the explosion is under investigation and authorities haven't released the children's names.