UFC champion Amanda Nunes will face challenger Irene Aldana at UFC 289 next month.
Julianna Peña was originally scheduled to face Nunes, but she will be unable to compete due to a rib injury. UFC President Dana White confirmed that Peña would not participate in the bout.
The new 135-pound matchup in Vancouver is set to headline the pay-per-view event.
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"Unfortunately, [Peña] broke her ribs and she can not compete," White said in an Instagram post.
"We have Irene Aldana coming in, who has won four of her last five and three of those were finishes. We could have another Mexican world champion."
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Aldana currently holds an 8-4 record in the UFC. She has won six of her past eight, with her most notable victory coming in 2019 via a first-round knockout of Ketlen Vieira.
On the losing end, Nunes suffered her most recent defeat to former champion Holly Holm in October 2020.
If Aldana is victorious, she would become the fourth active Mexican-born MMA champion. Flyweight Brandon Moreno, interim featherweight champ Yair Rodriguez, and flyweight Alexa Grasso make up the current group.
Aldana and Grasso are teammates at Lobo Gym.
Nunes is widely considered the world's top-ranked pound-for-pound female fighter. However, Peña was able to pull off an upset victory in December 2021.
In July 2022, Nunes dominated Peña in their second bout.
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Lightweights Charles Oliveira and Beneil Dariush are also set to go head-to-head in during the UFC 289 card. The event was initially scheduled for the first weekend in May but was postponed after Oliveira suffered an injury.