The injury bug as hit Jacob deGrom once again.

The Texas Rangers ace has been placed on the 15-day injured list with elbow inflammation.

DeGrom left his start against the New York Yankees Friday night with a trainer after just 3⅔ innings. It was regarded as forearm tightness, which is never a good sign. 

The Rangers inked deGrom to a high-risk, high-reward deal in the offseason.

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Jacob deGrom pitching

Texas Rangers starting pitcher Jacob deGrom delivers a pitch to the Oakland Athletics during the first inning of a game April 23, 2023, in Arlington, Texas. (AP Photo/Jim Cowsert)

The two-time Cy Young Award winner missed a majority of his final two seasons with the New York Mets with several different arm injuries. And when deGrom opted out of the final year of his deal, the Rangers were quick to sign him to a five-year, $185 million deal.

DeGrom had one of the greatest starts to a career in MLB history. From his MLB debut through his injury-shortened 2021 campaign, he had a 2.50 ERA. From 2018 to 2021, he was dominant.

In 91 starts during that span, his ERA was a miniscule 1.94. He earned back-to-back Cy Young Awards in 2018 and 2019, finished in third in 2020, and despite just 15 starts in 2021, finished in ninth with his 1.08 ERA that season. His 5.38 K/BB ratio is the best in major league history, and his 0.99 WHIP is the lowest among active starting pitchers.

Jacob deGrom on mound for Rangers

Jacob deGrom of the Texas Rangers pitches against the New York Yankees during the fourth inning at Globe Life Field April 28, 2023, in Arlington, Texas.  (Ron Jenkins/Getty Images)

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DeGrom, Clayton Kershaw and Greg Maddux are the only pitchers in MLB history to have a 1.95 ERA or less in a 100-start span. The only pitchers with an 80-start stretch of an ERA under 2.00 and 500-plus strikeouts are deGrom, Kershaw, Hal Newhouser, Bob Gibson, Sandy Koufax and Pedro Martinez.

However, in 2021 and 2022 combined, deGrom made just 26 starts, and he is on the shelf once again with a pitcher's worst nightmare of an injury.

Jacob deGrom pitches

Texas Rangers starting pitcher Jacob deGrom throws to a Kansas City Royals batter during the first inning of a game April 17, 2023, in Kansas City, Mo.  (AP Photo/Reed Hoffmann)

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DeGrom has a 2.67 ERA, an AL-best 13.4 K/9 and an MLB-best 1.63 FIP. In his first start, he allowed five earned runs in 3⅔ innings, but since then, he allowed just four earned in 26.2 innings (1.35 ERA).