The Kansas City Chiefs open the 2023 NFL season Thursday night against the Detroit Lions as they begin their title defense. 

They may be doing so without their four-time All-Pro tight end Travis Kelce after he suffered a hyperextended knee during Tuesday’s practice.  

Travis Kelce looks on field

Travis Kelce, #87 of the Kansas City Chiefs, reacts prior to an NFL preseason football game between the Arizona Cardinals and the Kansas City Chiefs at State Farm Stadium on August 19, 2023, in Glendale, Arizona. (Michael Owens/Getty Images)

Kansas City listed Kelce as questionable on Wednesday while Chiefs chairman and CEO Clark Hunt said he would be a game-time decision. 

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"I’ve never seen Travis as energized as I have this offseason. He’s been really dialed in. He’s been really busy off the field. Had a lot of things going on. But he’s also very focused on football, very excited about the upcoming season," Hunt said Thursday on "Good Morning Football." 

"I know we had a little bit of a setback the other day with a minor knee injury. We hope that he will be able to go tonight. He will be a game-time decision. But he’s somebody who loves to compete, so I wouldn’t bet against him being on the field tonight."

Kelce’s brother, Jason Kelce, said Wednesday that Kelce was experiencing some swelling in his knee. 

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Travis Kelce walks on field

Travis Kelce, #87 of the Kansas City Chiefs, reacts as he warms up prior to an NFL preseason football game between the Arizona Cardinals and the Kansas City Chiefs at State Farm Stadium on August 19, 2023, in Glendale, Arizona. (Michael Owens/Getty Images)

"Talked to him yesterday and I’ve done the same thing. You just plant, or you do something, and your knee hyperextends," Jason Kelce said Wednesday on the WIP Morning Show.

"I know he’s got some swelling going on, but it sounds like as long as they can keep that down, he’s gonna have a chance to go. The ligaments and everything are intact. Structurally, from what we know right now, his knee is fine. So, it’s really about getting that swelling down and seeing how bruised that bone is."

Kelce is coming off one his best seasons as a pro, ending the season with 110 receptions for 1,228 yards and 12 touchdowns. 

Detroit is entering the season with high expectations after going 9-8 in 2022 following a 1-6 start. 

Jared Goff vs Jaguars

Jared Goff, #16 of the Detroit Lions, looks on during the warmups before the preseason game against the Jacksonville Jaguars at Ford Field on August 19, 2023, in Detroit, Michigan.  (Nic Antaya/Getty Images)

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"The last two years, we haven’t started quick," quarterback Jared Goff said. "There’s a little bit of an increased awareness of it, I think, making sure that we don’t dig ourselves in a hole. But the same time, we’re trying to win every game."

Kansas City and Detroit kick off at 8:20 p.m. ET.