One of the frontrunners in men’s singles to win the 2024 U.S. Open has been knocked out in the second round. 

Spanish phenom Carlos Alcaraz, winner of the French Open and Wimbledon earlier this year, was shockingly upset in the second round by the Netherlands’ Botic Van De Zandschulp in straight sets. 

Van De Zandschulp, the 28-year-old from Wageningen, Netherlands, was only 87-83 in his career and 10-18 this year when he entered his match against Alcaraz after defeating Denis Shapovalov in the first round. 

CLICK HERE FOR MORE SPORTS COVERAGE ON FOXNEWS.COM

Carlos Alcaraz backhand

Carlos Alcaraz of Spain hits to Botic van De Zandschulp of the Netherlands on day four of the 2024 U.S. Open tennis tournament at USTA Billie Jean King National Tennis Center. (Robert Deutsch-USA TODAY Sports)

But it was clear from the start of the match that Van De Zandschulp was not at all nervous to be facing Alcaraz, the 21-year-old, four-time Grand Slam champion

Van De Zandschulp won the first set convincingly, 6-1, where Alcaraz airmailed a serve return over the baseline on triple set point. 

DEFENDING US OPEN CHAMPION COCO GAUFF SAYS SHE BLOCKS CYBERBULLIES ON SOCIAL MEDIA AMID PLAYER CONCERN

From there, the Spaniard kicked it up a notch, but Van De Zandschulp was still able to win the set via tiebreak, 7-5, to put himself in the driver’s seat to pull off the major upset. 

We’ve seen what Alcaraz can do with his back against the wall in the past, but Van De Zandschulp outlasted him yet again in the third set, finishing him off, 6-4, in front of a stunned New York City crowd. 

Carlos Alcaraz and Botic Van De Zandschulp shake hands

Botic van De Zandschulp of the Netherlands after beating Carlos Alcaraz of Spain on day four of the 2024 U.S. Open tennis tournament at USTA Billie Jean King National Tennis Center.  (Robert Deutsch-USA TODAY Sports)

Just like that, the No. 3-ranked men’s singles player in the tournament, and a large fan favorite, is out at the final Grand Slam of the year. Alcaraz had not lost at the U.S. Open before the quarterfinals in three previous appearances.

Alcaraz entered Thursday without losing in a Grand Slam in 15 matches. But, while Van De Zandschulp was exceptional, especially when the ball was on his forehand, it was a sloppy all-around performance by Alcaraz, who hurt himself too many times. 

Van De Zandschulp has faced Alcaraz two previous times, both of which were won by the Spaniard. However, serves from the lanky Dutchman were overpowering Alcaraz as they reached 132 mph on the radar. 

Carlos Alcaraz looks up on court

Spain's Carlos Alcaraz reacts during his men's singles first round match  against Australia's Li Tu on day two of the US Open tennis tournament at the USTA Billie Jean King National Tennis Center in New York City, on August 27, 2024.  (CHARLY TRIBALLEAU/AFP via Getty Images)

CLICK HERE TO GET THE FOX NEWS APP

As Alcaraz looks back at the tape to figure out what went wrong, Van De Zandschulp will move on to the third round, where he’ll face another ranked opponent – No. 25 Jack Draper from Great Britain. 

Follow Fox News Digital’s sports coverage on X, and subscribe to the Fox News Sports Huddle newsletter.