Selena Gomez has been transparent about both her mental and physical health challenges over her more than two decades in the industry, but the actress turned pop star is revealing for the very first time another heartbreaking obstacle she's had to work through.

"I haven’t ever said this," the "Emilia Perez" star told Vanity Fair. "But I unfortunately can’t carry my own children. I have a lot of medical issues that would put my life and the baby’s in jeopardy."

"That was something I had to grieve for a while."

SELENA GOMEZ ADMITS LOSING 'TEENAGER'S BODY' LEFT HER 'EMBARRASSED,' LED TO RELENTLESS BODY SHAMING

Selena Gomez in a black dress looks directly at the camera with lights set up behind her

Selena Gomez revealed that due to "medical issues," she won't be able to carry her own child, but the "Emilia Perez" star is confident there are other avenues to pursue to start a family. (KC Armstrong/Deadline via Getty Images)

In 2013, Gomez was diagnosed with lupus, an autoimmune diease where the body attacks its own healthy tissue. She underwent chemotherapy and in 2017, at age 24, she had a kidney transplant, due to complications from the disease.

"It’s not necessarily the way I envisioned it," Gomez continued of her path to motherhood. "I thought it would happen the way it happens for everyone. [But] I’m in a much better place with that. I find it a blessing that there are wonderful people willing to do surrogacy or adoption, which are both huge possibilities for me."

Selena Gomez smiles for the camera in a halter black lace dress on the carpet

Selena Gomez says she's grateful there are other ways to expand a family, including adoption and surrogacy. (Kevin Winter/Getty Images)

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Gomez's family has already been impacted by the latter. Her mother, Mandy Teefey, was adopted. "I probably wouldn’t be here [if my mom wasn't adopted.] I don’t know what her life would’ve been like. She and I are very thankful for how life played out."

In terms of having options, the "Only Murders in the Building" star is grateful. "It made me really thankful for the other outlets for people who are dying to be moms. I’m one of those people," she admitted. "I’m excited for what that journey will look like, but it’ll look a little different. At the end of the day, I don’t care. It’ll be mine. It’ll be my baby."

Selena Gomez in a plum strapless gown at the Emmy Awards

Even before she was in a relationship, Selena Gomez, 32, envisioned starting her family at 35. (Gilbert Flores/Variety via Getty Images)

Up until July 2023, when she met her now boyfriend, music producer Benny Blanco, Gomez had been single for five years. Even without a partner, Gomez says she'd intended to expand her family by 35.

Selena Gomez and Benny Blanco attend a basketball game

Selena Gomez and her boyfriend Benny Blanco started dating in 2023. They started as friends and then their relationship turned romantic. (Allen J. Schaben/Los Angeles Times via Getty Images)

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"Before I met my boyfriend, I was single for five years, with the exception of going on a few dates," she disclosed. "And I was like, ‘OK, if this is the vibe, then what is the most important thing to me? Family.’"

Gomez, who has been linked to several other high-profile stars, including Justin Bieber, The Weeknd and Nick Jonas, raved about her relationship with Blanco. "I’ve never been loved this way," she said. "He’s just been a light. A complete light in my life. He’s my best friend. I love telling him everything."

Selena Gomez in a black leather jacket soft smiles as her boyfriend Benny Blanco, wearing a sweatshirt, wraps his arms around her

Selena Gomez gushed about Benny Blanco, her boyfriend of more than a year. (Selena Gomez Instagram)

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And even though things are going well between the couple, Gomez says she isn't in a rush to get married. "We always make sure we’re protecting what we have, but there’s no rules," she said. "I want him to always be himself. I always want to be myself."

Being herself also means no future name deviations. "I’m not changing my name no matter what. I am Selena Gomez. That’s it."