Ryan Seacrest will close out 2020 with a special pair of guests by his side: the president-elect and the future first lady.

Joe Biden and his wife, Dr. Jill Biden, are scheduled to appear at this year's "Dick Clark's New Year's Rockin' Eve" alongside Seacrest.

The Bidens will "share an inspiring message as we come together to close out 2020 and look ahead with hope to 2021," according to a statement by the producers.

Jennifer Lopez will be the musical headliner. The pop star will perform live before the iconic ball drop on Dec. 31. Because of the coronavirus pandemic, the event will be closed to the public.

STARS WHO GOT POLITICAL IN SURPRISING WAYS IN 2020

Performers in Los Angeles include Brandy, Doja Cat, Ella Mai, En Vogue, Julia Michaels & JP Saxe, Lewis Capaldi, Maluma, Megan Thee Stallion, Miley Cyrus, Nelly and Saweetie. New Orleans natives Big Freedia and PJ Morton will appear from that city.

Ryan Seacrest will be joined by president-elect Joe Biden and his wife, Dr. Jill Biden, on Thursday night for the 'New Year's Rockin' Eve' event.

Ryan Seacrest will be joined by president-elect Joe Biden and his wife, Dr. Jill Biden, on Thursday night for the 'New Year's Rockin' Eve' event. (Evan Agostini/Invision/AP)

Other performers in New York include Cyndi Lauper, Billy Porter, Jimmie Allen and Machine Gun Kelly. Lauper and Porter collaborated on the Broadway musical "Kinky Boots" and will join forces for a performance during the TV special, which kicks off on ABC at 8 p.m. Eastern.

CLICK HERE TO GET THE FOX NEWS APP

"Dick Clark’s New Year’s Rockin’ Eve with Ryan Seacrest 2021" will run until 2 a.m. Eastern on Jan. 1. Seacrest is returning to host the event for a 16th year, and will be joined by Porter and Lucy Hale in New York. Ciara will host from Los Angeles.

The Associated Press contributed to this report.