Methamphetamine is killing more Americans each year and health workers are worried about it. 

The drug is more popular – and more deadly – these days, leaving health officials and police scrambling to limit its spread.

"It really has taken off… and what’s really happened the last five years is it’s started to be mixed with opiates," said University of Washington Physician Paul Borghesani.

Borghesani monitors drug trends in the U.S. and has noticed increasing dangers in methamphetamine, a stimulant, being combined with depressive drugs like heroin or fentanyl.

BORDER AGENTS SEIZE 200 POUNDS OF 'LIQUID METH' HIDDEN IN TRACTOR FUEL TANK: 'TRAFFICKERS WILL TRY ANYTHING'

Bags of meth

More methamphetamine is coming into the U.S. from the southern border. (Fox News)

"When you mix the two, you’re kind of giving a mixed message to the body," Borghesani said." Which can make it quite lethal, because you kind of get picked up sometimes and then crash off of it."

ARIZONA TROOPERS RECOVER $1.3 MILLION WORTH OF FENTANYL, METH IN DRUG BUST

The most recent data from the American Public Health Association shows a dramatic increase in deaths caused by this combination.

In 1999, meth killed 608 people, according to the APHA. In 2021, that number was around 52,400 – and 61% of those fatal meth overdoses involved either heroin or fentanyl.

Increase in deaths associated with meth

The number of deaths caused by methamphetamine has skyrocketed over the last 20 years. (Fox News)

"America is being inundated with methamphetamine, with synthetic drugs like fentanyl," said former DEA Special Operations Director Derek Maltz. "And our citizens across the country are being harmed at historic levels."

FLORIDA DRUG DEALER SUSPECTED OF METH TRAFFICKING ARRESTED FOR 25TH TIME: POLICE

Maltz has been tracking the methamphetamine increase in the U.S. He’s noticed more of the drug coming up from the southern border and making its way into local communities.

More communities are getting exposed to meth

Methamphetamine is becoming more common in local communities. (Fox News)

"The cartels are bringing liquid meth into America," Maltz said. "They’re setting up labs to convert the liquid meth into the crystal meth that’s out on the streets." 

CLICK HERE TO GET THE FOX NEWS APP

The CDC reports methamphetamine has passed cocaine as the second most common drug involved in overdose deaths within the last three years.