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Ice Cube is making it clear he has no affiliation with Sean "Diddy" Combs after the disgraced mogul’s arrest earlier this month.

The rapper was performing for a crowd in Las Vegas Sunday, where he denied ever attending a party hosted by Combs.

"Almost 40 years rocking the mic, and I’m gonna tell you right now, me and [rapper] W.C. ain’t never been to a Diddy party," he told the audience in a video shared on social media.

The audience cheered, and someone yelled, "Thank God."

Ice Cube standing on stage with a microphone

Ice Cube told an audience at a recent performance he "ain’t never been to a Diddy party." (Theo Wargo/Getty Images)

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"You ain’t gotta worry about us on them mother----ing tapes," the rapper added.

Representatives for Ice Cube did not immediately respond to Fox News Digital’s request for comment.

WARNING: VIDEO LINK CONTAINS GRAPHIC LANGUAGE 

Combs was arrested Sept. 17, charged with racketeering conspiracy; sex trafficking by force, fraud or coercion; and transportation to engage in prostitution. He faces a minimum of 15 years behind bars and a maximum sentence of life in prison if found guilty.

The 54-year-old pleaded not guilty in a Manhattan court, where he was denied the proposed $50 million bail and sent to jail immediately after the hearing.

Sean Diddy Combs wears white cardigan

Sean "Diddy" Combs was charged with racketeering conspiracy; sex trafficking by force, fraud or coercion; and transportation to engage in prostitution. (Munawar Hosain)

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Authorities claimed Diddy ran a criminal enterprise through his businesses, including Bad Boy Entertainment, Combs Enterprises and Combs Global, among others. He used "violence, use of firearms, threats of violence, coercion, and verbal, emotional, physical, and sexual abuse" to fulfill his sexual desires, according to an unsealed indictment obtained by Fox News Digital. 

In the indictment, Combs is alleged to have recorded "freak offs," described by authorities as "elaborate and produced sex performances that Combs arranged, directed, masturbated during, and often electronically recorded.

"Almost 40 years rocking the mic, and I’m gonna tell you right now, me and W.C. ain’t never been to a Diddy party."

— Ice Cube

"Combs also used the sensitive, embarrassing, and incriminating recordings that he made during Freak Offs as collateral to ensure the continued obedience and silence of the victims," according to the indictment.

Ice Cube is one of a small handful of celebrities speaking out against Combs after Combs' arrest.

WATCH: US ATTORNEY GIVES PRESS CONFERENCE ON DIDDY'S SEX TRAFFICKING CHARGES

DIDDY SEX TRAFFICKING PROBE: HOLLYWOOD STARS ARE 'SCARED TO DEATH' TO SPEAK OUT, EXPERTS SAY

Aubrey O’Day, 50 Cent, Shyne, Kesha and Mary J. Blige have all commented on the allegations against Combs in one form or another.

"Given the severity of the charges, the detailed allegations in the indictment and the long-standing rumors surrounding Combs, there's no shortage of reasons why celebrities would choose to remain silent for the time being," Doug Eldridge, founder of Achilles PR, told Fox News Digital.

Interviews with Combs have also recently resurfaced in which the "Bad Boy for Life" rapper talks about his parties.

Sean "Diddy" Combs standing on a balcony wearing all white

Combs alluded to wild activity in two different resurfaced interviews. (Bryan Bedder/CP/Getty Images for CP)

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In a 1999 interview with Entertainment Tonight, Combs said, "You’re gonna hear about my parties. They’re going to be shutting them down. They’re probably going to be arresting me doing all types of crazy things just because we want to have a good time, you know?"

Combs also explained the "ingredients" for a "killer party" in a 2002 interview on "Late Night with Conan O’Brien."

"Women, beautiful women, of course," Combs shared with O’Brien. "Beautiful men for the ladies, of course."

Diddy

In one interview, Combs said, "You’re gonna hear about my parties. They’re going to be shutting them down. They’re probably going to be arresting me doing all types of crazy things just because we want to have a good time, you know?" (Getty Images)

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He continued to say that "alcohol" is a requirement at the party, in addition to water. 

"A lot of ladies drink water at parties. So, if you don’t have what they need, they’re going to leave. Got to keep them there. You need locks on the doors. It’s a little kinky."