Detroit could be the latest big city to decriminalize "magic mushrooms" and other psychedelics drugs as residents take to the polls Tuesday. 

Voters will be asked under proposal E: "Shall the voters of the City of Detroit adopt an ordinance to the 2019 Detroit City Code that would decriminalize to the fullest extent permitted under Michigan law the personal possession and therapeutic use of Entheogenic Plants by adults and make the personal possession and therapeutic use of Entheogenic Plants by adults the city's lowest law-enforcement priority?"

About 40 miles west of Detroit, the city council in Ann Arbor, home to the University of Michigan, unanimously voted to decriminalize a wide range of psychedelic drugs last year. 

Several other big cities throughout the United States have also decriminalized psychedelics, including Seattle, Denver, Washington, D.C., Oakland, and Santa Cruz. 

Entheogenic plants – which include drugs such as psilocybin mushrooms, mescaline, and ayahuasca – are described in proposal E as "the full spectrum of plants, fungi, and natural materials and/or their extracted compounds, limited to those containing the following types of compounds: indole amines, tryptamines, and phenethylamines." 

SEATTLE CITY COUNCIL UNANIMOUSLY SUPPORTS DECRIMINALIZING PSYCHEDELIC DRUGS

"While the DEA considers them to have a potential for abuse, others believe them to have medicinal value for treatment of depression and pain and other maladies, religious significance, and accompanied by a low propensity for abuse," the proposal reads. 

The plants are difficult to study because they are federally classified as schedule 1 drugs, but some researchers have found that psilocybin mushrooms could reduce depression and anxiety in cancer patients, MDMA could reduce symptoms of PTSD, and LSD could help treat alcoholism

Psilocybin or "magic mushrooms" are seen in an undated photo provided by the U.S. Drug Enforcement Agency (DEA) in Washington, U.S. May 7, 2019. DEA/Handout via REUTERS.  

Psilocybin or "magic mushrooms" are seen in an undated photo provided by the U.S. Drug Enforcement Agency (DEA) in Washington, U.S. May 7, 2019. DEA/Handout via REUTERS.  

Harvard Law School launched the Project on Psychedelics Law and Regulation this summer to examine the legal framework around psychedelic research. 

"Preliminary research suggests that psychedelics could hold major benefits for people experiencing trauma and post-traumatic stress disorder," Harvard Law professor Jeannie Suk Gersen said in a statement. 

"By analyzing social, legal, and political barriers to access in this context, we hope to advance the understanding of their potential impact as therapeutics."

A spokesperson for the Detroit Police Department told Fox News that they "have not taken a position on the ordinance at this time."

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Wayne County Prosecutor Kym Worthy did not respond to a request for comment on Tuesday. 

In September, state Senator Adam Hollier of Detroit and Jeff Irwin of Washtenaw County introduced a bill that would decriminalize psychedelic drugs statewide. 

Fox News's Audrey Conklin contributed to this report.