Updated

In a stunning upset, Serena Williams, the No. 10-ranked women's tennis player in the world, was defeated in the third round of the French Open by fellow American Sofia Kenin, becoming the latest high-profile player to lose in the tournament.

Williams, 37, lost to the 20-year-old Kenin in straight sets, 6-2, 7-5, on Saturday, hours after the top-seed Naomi Osaka suffered her own shocking defeat and first Grand Slam loss since last July.

Serena Williams of the U.S. reacts after missing a shot against Sofia Kenin of the U.S. during their third round match of the French Open tennis tournament at the Roland Garros stadium in Paris, Saturday, June 1, 2019.

Serena Williams of the U.S. reacts after missing a shot against Sofia Kenin of the U.S. during their third round match of the French Open tennis tournament at the Roland Garros stadium in Paris, Saturday, June 1, 2019. ((AP Photo/Christophe Ena ))

Kenin, the 35th-ranked player in the world, is a big hitter who never made it past the fourth round of a major tennis tournament in eight previous appearances. She had never won a French Open match until this year.

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It was the earliest Serena had lost in a major since 2014, when she was defeated in the third round at Wimbledon to Alize Cornet.

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Williams hopes to bounce back next month at Wimbledon, a place where she's won seven majors since 2002.