Updated

By Steve Keating

INDIANAPOLIS (Reuters) - Peyton Manning gave younger brother Eli a quarterback master class by tossing three touchdowns to lead the Indianapolis Colts of a 38-14 victory over the New York Giants on Sunday.

While the quarterback siblings both have Super Bowl rings and Super Bowl MVP awards on their resumes, Peyton is the only one with a "Manning Bowl," maintaining his vice-like grip on family bragging rights with the rout.

Much has changed since 2006 when Peyton and Eli became the first and only brothers to start against each other at quarterback in an NFL game but the one thing that has remained the same is the senior Peyton's domination.

The older Manning was superb in the Colts home opener, taking control from their first possession, completing 20 of 26 passes for 255 yards. His three touchdown passes boosted his total to six on the young season.

Peyton was backed up by a punishing defense that mercilessly harassed his little brother all night, twice forcing fumbles that were converted into touchdowns.

Back on the same field for the first time in four years, Manning Bowl II was given the full prime time television treatment.

Even the Mannings, reluctant participants in the hype surrounding their first meeting won 26-21 by the Colts at Giants Stadium, embraced the showdown as something special, even helping promote the game with a commercial poking fun at each other.

But there were few smiles and even less brotherly love once play got underway.

The Colts had the ball first and Peyton went to work with his little brother watching from the sidelines hands on hips.

Peyton immediately threw down the gauntlet, engineering an 80-yard scoring drive, completing all five of his pass attempts before Donald Brown scampered the final seven yards for the TD.

Manning had the Colts on the march again early in the second quarter, capping a 98-yard drive with a floating 50-yard touchdown strike to Dallas Clark.

A vicious Colts defense kept Eli under constant pressure forcing two turnovers in the second quarter, which Peyton converted into points and a 24-0 halftime lead.

Jerraud Powers intercepted Manning and Peyton quickly made his little brother pay for the mistake moving the ball into range for a 38-yard Adam Vinatieri field goal.

A miserable half for the Giants ended with the Colts forcing a fumble from Manning and Peyton finding Austin Collie for a three-yard touchdown.

Eli flashed his quarterbacking credentials when he opened the second half with a 54-yard touchdown pass to Mario Manningham.

But the Colts defense wasted no time ending any thoughts of comeback, Dwight Freeney sacking the Giants quarterback and Fili Moala scooping up the loose ball in the end zone.

Manning then hit Reggie Wayne eight-yard touchdown while Eli replied with a 31-yard strike to Hakeem Nicks to close out the scoring.

(Editing by Steve Ginsburg/Alastair Himmer)