<b>Manny Ramírez</b>
The slugging outfielder <a target="_blank" href="http://latino.foxnews.com/latino/sports/2011/04/08/manny-ramirez-retires-mlb-drug-policy-issue/">abruptly retired after he reportedly was facing a second PED</a> suspension. (AP)
<b>Rafael Palmeiro</b>
The infamous finger wagging, a lasting image in Palmeiro's career. It probably hurt <a target="_blank" href="http://latino.foxnews.com/latino/sports/2011/01/05/alomar-elected-hall-fame-palmeiro-gonzalez/">his Hall of Fame</a> chances. (AP)
<b>Alex Rodríguez</b>
A-Rod's career has been uneven: brilliant numbers, marred by a PED admission. He's still <a target="_blank" href="http://latino.foxnews.com/latino/sports/2011/02/28/hank-aaron-questions-alex-rodriguez-focus-baseball/">the favorite to break the all-time home run record</a>. (AP2011)
<b>David Ortiz</b>
The Red Sox slugger was Ramirez's partner in, um, crime. (AP2011)
<b>Miguel Tejada</b>
Tejada was mentioned in the Mitchell Report. (2011 Getty Images)
<b>J. C. Romero</b>
The lefty specialist was suspended for 50 games in the 2009 season. (2010 Getty Images)
<b>Guillermo Mota</b>
The hard-throwing reliever was suspended 50 games for a steroid violation in 2006. (AP2011)
<b>Neifi Pérez</b>
The utility infielder has been busted three times. (2006 Getty Images)