St. Louis, MO – Brad Marchand scored twice as Boston doubled 2, at Scottrade Center.
Chris Kelly and Milan Lucic each posted a goal and one assist for the Bruins, who had lost three of four coming in.
Tim Thomas stopped 30-of-32 shots for the win.
Chris Stewart and Ryan Reaves tallied for the Blues, who have dropped two in a row.
Brian Elliott was shelled for four goals on only 19 shots in defeat.