Updated

The federal government wants doctors to run more tests on infants born to mothers possibly infected with the Zika virus, which is spreading in Miami.

The Centers for Disease Control and Prevention updated its clinical guidance on Friday to reflect new information on the virus. It is giving doctors new information on how to interpret laboratory testing on infants and it wants doctors to increase their vigilance in examining the babies through repeated eye and hearing tests and ultrasounds.

More than 500 women have shown evidence of the Zika virus across the U.S., with 16 infants having birth defects, according to CDC data as of Aug. 11.

In the U.S. territory of Puerto Rico, the virus has been spreading via mosquito bites for some time. A new study published Friday estimates that up to 10,300 pregnant women could have been infected with Zika during the initial outbreak.

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