Marion "Suge" Knight is in custody, charged with murder after the truck he was driving ran over two men in the parking lot of Compton restaurant Tam's Burgers, killing his friend Terry Carter.

The incident happened Thursday after a commercial shoot for the upcoming film "Straight Outta Compton." The movie chronicles the rise of pioneering rap group N.W.A, comprised of Arabian Prince, Eazy-E, Dr. Dre, DJ Yella, Ice Cube and later MC Ren.

N.W.A. put out their recordings on Death Row records, founded by Knight and Dre.

Knight was not involved in the promotional shoot, nor was he invited to it, sources tell FOX411. Dre and Cube were there for the promotional filming, but were not present at the incident at Tam's Burgers.

According to a source connected to Knight, the film had re-ignited simmering tensions between Knight and Dre.

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"The movie was stirring up a lot of old issues between them that had kind of dissipated. It was recreating a lot of animosity," the insider told FOX411. "Suge wasn't in agreement with a lot of the script. And along with that, he has a pretty short fuse."

Another source concurred that Dre and Knight have "been at odds for years," and that reports of ongoing conflict between the two would not be surprising.

According to TMZ, Knight was trying to get to the set to make peace with Dre, and that Knight's friend Carter was the go-between. Dre's camp, however, told TMZ that Dre's security had Knight removed from another set location, as having him around makes everyone a target.

While attending a pre-VMAs party hosted by Chris Brown last summer, Knight was shot multiple times.

"Dre is the type of guy who is a straight shooter -- not literally -- and Suge is not," one well-placed music industry insider explained.

In 1996, Knight was driving a BMW in Las Vegas when his passenger, popular rapper Tupac Shakur, was fatally shot by gunmen in another vehicle. Despite rumors of Knight's involvement in Shakur's death, he was never convicted and the case remains unsolved.

Universal, the studio behind "Straight Outta Compton," has been quick to distance itself from Thursday's deadly incident. A source connected to the project but not authorized to speak on the topic told FOX411 that filming wrapped in October and the film is still slated to be released in August as initially planned.

A representative for Knight did not immediately respond to comment requests, and a publicist for Dre declined to comment.

Law enforcement officials confirmed that Knight ran over two people on Thursday afternoon, killing one and injuring another. His attorney James E. Blatt said it was an act of self-defense as he was being attacked by a group. But witnesses told police that the driver hit the men with his truck, then backed over them again before fleeing the scene.

Knight is currently being held in Los Angeles in lieu of $2 million bail.