Real-Life 'Benjamin Buttons'

Brad Pitt in 2005 (l) and 2008 (r). Pitt, 45, is the only man on Earth who can age backwards while acquiring six children in the span of three years. He truly is 'Benjamin Button.' Now we know why they cast him - to save on makeup and special effects. It was all real... (AP)

Carson Daly in 2002 (l) and 2007 (r). The 35-year-old Daly went from staying out late at night with girlfriend Tara Reid to hosting a late night talk show. The secret to eternal youth. (AP)

Tom Cruise in 2006 (l) and 2009 (r). Maybe Scientologists all age backwards? If that's the case, we're interested. (AP)

Johnny Depp in 1998 (l) and 2008 (r). A decade passed between these two photographs, yet Depp, 45, looks exactly the same, if not younger. It's probably from living in France - French people do not age. It's a scientific fact. (AP)

Patrick Dempsey in 2001 (l) and 2008 (r). The 43-year-old actor also lost that dent in his forehead! Will 'Benjamin Button' miracles never cease. (AP)

Kevin Coster in 2003 (l) and 2008 (r). We suspect elective surgery and Hair Club For Men may be the 53-year-old Costner's 'Benjamin Button' secret. It's just a guess... (AP)

Will Ferrell in 2003 (l) and 2008 (r). The 41-year-old funnyman proves that not only does laughter keep you young, it can make you get younger. (AP)

George Clooney in 2000 (l) and 2008 (r). Clooney's 'Benjamin Button' secret is simple: the 47-year-old star never got married. (AP)