Andrew Shue: After hitting it big as Billy Campbell on "Melrose Place" (1992-1999) Andrew Shue, 41, basically bid adieu to Hollywood. He now runs several successful businesses including Do Something and CafeMom, a social networking site specifically targeted at mothers. (FOX)
We know what the ladies are up to, but what exactly became of the fellas from the 90's mega hit "Friends?" Matt Le Blanc (aka Joey Tribbiani), 41, has not appeared onscreen since Friends spin-off Joey was cancelled in 2006 to concentrate on his own production company, Fort Hill Productions. David Schwimmer (aka Ross Geller, 42, has gone on to find success in the world of directing. He directed the British comedy "Run, Fat Boy, Run" in 2007, which topped the UK box office and is currently directing in-studio segments for "Little Britain USA." Matthew Perry (aka Chandler Bing), 39, went on to appear in several small movies and Matthew is now working on "The End of Steve," a dark comedy he wrote and produced with Peter Tolen, which has been picked up by Showtime and will feature Perry playing an unhappy, egomaniacal TV talkshow host (NBC)
James Van Der Beek: Van Der Beek, 31, hit heartthrob status playing the title character on "Dawson's Creek" (1998-2003) and with roles in edgier flicks such as "Varsity Blues" and "The Rules of Attraction." Since the show ended he completed his first screenplay, "Winning," and had guest roles on "Ugly Betty," "How I Met Your Mother," and more recently, "One Tree Hill." In November 2008, it was reported that he will co-star on "Eva Adams," an upcoming Fox drama pilot. (CW)
Jonathan Taylor Thomas: The role of Randy Taylor on "Home Improvement" (1991-1998) catapulted Jonathan Taylor Thomas, 27, to teen-idol status. After the show he had guest roles on "8 Simple Rules for Dating My Teenage Daughter," "Smallwille," and "Veronica Mars." He is now engaged and enrolled in the Bachelor's Degree Program for General Studies at Columbia University. (BC)
Kellie Shanygne Williams: She had Steve Urkell in a constant tizzy as Laura Winslow on "Family Matters" (1989-1997). These days Kellie, 32, spends her time working with various projects and youth foundations. She also has a movie coming out in May 2009, "Steppin: The Movie," also featuring other "Family Matters" alums like Reginald VelJohnson (Carl Winslow) and Darius Creston McCrary (Eddie Winslow). (ABC)
Mayim Bialik: After a successful run playing the title character on "Blossom" (1991-1995), Mayim Bialik, 32, got married, had two kids, and received a PhD. in neuroscience from UCLA. She hasn't given up acting entirely and has made appearances on "Curb Your Enthusiasm" and "Fat Actress." (NBC)
Neve Campbell: Campbell rose to fame playing Julia Salinger in the drama series "Party of Five" (1994-2000) and dominated in the 90's with a steady stream of hit movie including "The Craft," the "Scream" trilogy, and of course, "Wild Things." She is now married and will reportedly reprise her role as Sidney Prescott in "Scream 4" due in July 2010. (FOX)
Rider Strong: Strong, 29, found fame as loveable bad boy Shawn Hunter on "Boy Meets World" (1993-2000). He wrote and directed the short film "Irish Twins" along with his brother Shiloh which premiered at the 2008 Tribeca Film Festival and picked up a slew of awards. (NBC)
Tia and Tamara Mowry: This dynamic duo played twins separated at birth on "Sister, Sister" (1994-1999). Now 29, Tia currently stars in the CW series "The Game" and both girls will co-star in the upcoming flick "Hollywood Horror," with Haylie Duff. (CW)
Tiffani Thiessen: Thiessen, 34, dominated in the 90's with roles as good girl Kelly Kapowski on "Saved by the Bell" (1989-1992) and vixen Valerie Malone on "Beverly Hills, 90210" (1990-2000). She costarred in the short-lived drama "What About Brian" in 2007 and has been cast in "White Collar," a new USA pilot. ( )